Everyone that came into this world entered through God’s design. And each person has an assignment from God. You were sent into this world by God to accomplish a specific mission.

“Therefore, when Christ came into the world, he said: ‘Sacrifice and offering you did not desire, but a body you prepared for me; with burnt offerings and sin offerings you were not pleased. Then I said, ‘Here I am- it is written about me in the scroll- I have come to do your will, O God.’”
~ Hebrews 10: 5-7  

God has prepared a body for you, to enable you execute His specific assignment for your life. This prepared body is not only your physical body, but also the people who have been designated by God to help you carry out your God-given mission. Your God-given assignment requires the participation of other people; and so, God has prepared a community of people whom He gifted to assist you in that assignment.

These people that God has assigned to your mission are your body and also your family, as Jesus showed us during His days on earth:

“While Jesus was still talking to the crowd, his mother and brothers stood outside, wanting to speak to him. Someone told him, ‘Your mother and brothers are standing outside, wanting to speak to you.’ He replied to him, ‘Who is my mother, and who are my brothers? Pointing to His disciples, he said, ‘Here are my mother and my brothers. For whoever does the will of my Father in heaven is my brother and sister and mother.
~Matthew12:46-50

Jesus saw His disciples who were assisting Him in His God-given mission, as family. He was absolutely clear on that. He had no sentiment to waste on people who were not a part of that group, including his biological siblings! Actually, on another occasion, He made this statement:

“He who is not with me is against me, and he who does not gather with me scatters.”
~Matthew 12:30

Jesus was very focused in His relationships. You should do the same. There is no point wasting your time, energy and resources on unproductive relationships that will not enable you to accomplish your God-given mandate. Like Jesus, focus on your assignment and on the people who are connected to it.